| BIOL 615 Systematic & Comparative Biology - Fall 2008 | |||
| Lectures: | |||
| 5 Sept . Fri | Introductions, syllabus (note - class meeting time changes to T/TH 9:45 - 11:15) | ||
| 9 Sept. Tues | Taxonomy, classification, The Modern Synthesis, basic nomenclature | Mayr 1991 Ch. 1 pp. 1-18 | |
| 11 Sept. Thurs | Journal article discussion - TBA | ||
| 16 Sept. Tues | Taxonomy and classification prior to 1859: Pre-Socratic philosophers to Darwin | Mayr 1982 Ch. 4 pp. 147-208; 7 & 8 pp. 301-371 | |
| 18 Sept. Thurs | Evolutionary classification, phenetics, cladistics: 1859 - present | Mayr 1982 Ch. 5 pp. 209-250; 8 pp. 371-393 & Mayr 1991 Ch. 8-10 | |
| 23 Sept. Tues | Journal article discussion - TBA |
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| 25 Sept. Thurs | Systematic collections, publication, rules of zoological nomenclature | Mayr 1991 Ch. 12-14 pp. 325-406 | |
| 30 Sept. Tues | Journal article discussion - TBA | ||
| 2 Oct. Thurs | Parsimony, rooted and unrooted phylogenetic trees | Felsenstein Ch. 1 pp. 1-10 | |
| 7 Oct. Tues | Tree search algorithms: Exhaustive, heuristic, and branch and bound searches | Felsenstein Ch. 2-5 pp. 11-66 | |
| 9 Oct. Thurs | PAUP* 4.0/MacClade demonstration | ||
| 14 Oct. Tues | Journal article discussion - TBA | ||
| 16 Oct. Thurs | Ancestral character states, branch lengths, types of parsimony, character weighting, consenus trees, and Bremer support | Felsenstein Ch. 6-7 pp. 67-86; Ch. 30 pp. 521-528, 535-538, Ch. 19 330-331 | |
| 21 Oct. Tues | Distance matrix methods: Least squares, UPGMA, neighbor-joining | Felsenstein Ch. 10-11, pp. 123-155, 159-175 | |
| 23 Oct. Thurs | Journal article discussion - TBA | ||
| 28 Oct. Tues | Models of DNA and protein evolution | Felsenstein Ch. 11 pp. 156-159, Ch. 13-14 pp. 196-229 | |
| 30 Oct. Thurs | Journal article discussion - TBA | ||
| 4 Nov. Tues | Statistical properties of parsimony,maximum likelihood | Felsenstein Ch. 9 pp. 97-122, Ch. 16 pp. 248-256 | |
| 6 Nov. Thurs | Maximum likelihood cont. | Felsenstein Ch. 16 pp. 256-274 | |
| 11 Nov. Tues | Journal article discussion - TBA | ||
| 13 Nov. Thurs | Bayesian inference of phylogeny, MrBayes 3.0 demonstration | Felsenstein Ch. 18 pp. 288-306 | |
| 18 Nov. Tues | Journal article discussion - TBA | ||
| 20 Nov. Thurs | Likelihood ratio tests, testing molecular clocks, ModelTest 3.5 demonstration | Felsenstein Ch. 19 pp. 307-334 | |
| 25 Nov. Tues | Journal article discussion - TBA | ||
| 27 Nov. Thurs | Thanksgiving (no class) | ||
| 2 Dec. Tues | Bootstrap, jacknife, permutation tests, paired-sites tests | Felsenstein Ch. 20 pp. 335-363, Ch. 21 pp. 364-372 | |
| 4 Dec. Thurs | Journal article discussion - TBA | ||
| 9 Dec. Tues | Sequence alignment; Clustal X and POY 3.0 demonstration/comparison | Felsenstein Ch. 29 pp. 496-520 | |
| 11 Dec. Thurs | Class manuscript presentations | ||
| Location and time: | |||
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Tues & Thurs 9:45
- 11:15 AM, 103 Irving 1 |
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| Required text: | |||
| Felsenstein, J. 2004. Inferring Phylogenies. Sinauer Associates, Sunderland, Massachusetts. |
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*See list of typos at http://evolution.gs.washington.edu/book/typos.html |
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| Other useful texts: | |||
| Mayr, E. 1969. Principles of Systematic Zoology. McGraw-Hill, New York. | |||
| Mayr, E. 1982. The Growth of Biological Thought. Harvard University Press, Cambridge, Massachusetts. | |||
| Hillis, D. M., C. Moritz, and B. K. Mable. 1996. Molecular Systematics. Sinauer Associates, Sunderland, Massachusetts. | |||
| Course requirements: | |||
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| Grading: | |||
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| Journals: | |||
| Cladistics | |||
| Evolution | |||
| Genetics | |||
| Journal of Molecular Evolution | |||
| Molecular Biology and Evolution | |||
| Molecular Ecology | |||
| Molecular Phylogentics and Evolution | |||
| Nature | |||
| Proceedings of the National Academy of Sciences | |||
| Science | |||
| Systematic Biology | |||
| Trends in Ecology and Evolution | |||
| Other useful links: | |||
| abebooks.com | |||
| Animal Diversity Web | |||
| GenBank | |||
| Joe Felsenstein's List of Phylogeny Programs | |||
| PAUP* 4.0 | |||
| MacClade 4.0 | |||
| MrBayes 3.1 | |||
| Oxford Evolutionary Biology Group Software | |||
| Tree of Life Web Project | |||
| UAF Journals List | |||
| UC Berkeley Phylogeny Site | |||
| Web of Science | |||
| Contact information: | |||
Kevin
G. McCracken |
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| Office hours: | |||
| Monday-Wednesday 3:30 to 4:30 pm or by appointment | |||